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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCNX
All Species:
1.52
Human Site:
S220
Identified Species:
2.78
UniProt:
Q96RV3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RV3
NP_055797.2
2341
258676
S220
V
S
N
D
S
F
I
S
I
Q
P
S
L
S
S
Chimpanzee
Pan troglodytes
XP_510039
2300
254005
C218
D
Q
S
L
S
S
A
C
D
T
E
V
A
S
L
Rhesus Macaque
Macaca mulatta
XP_001084081
2342
258864
I221
S
N
D
S
F
I
S
I
Q
P
S
L
S
S
C
Dog
Lupus familis
XP_537501
2332
257280
S228
Q
D
L
P
R
D
F
S
D
K
V
S
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYC1
2344
258128
Q222
N
D
S
F
I
S
I
Q
P
S
L
S
S
C
G
Rat
Rattus norvegicus
NP_001163818
2343
257924
Q222
N
D
S
F
V
S
I
Q
P
S
L
S
S
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423893
2312
255194
L221
C
D
T
E
V
A
S
L
I
T
L
H
S
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923995
2285
252748
H221
C
D
T
E
I
T
A
H
L
S
T
H
S
Q
S
Tiger Blowfish
Takifugu rubipres
Q98UF7
1703
191329
Fruit Fly
Dros. melanogaster
P18490
3433
367590
E492
T
K
S
D
L
G
I
E
Q
P
H
Q
P
T
F
Honey Bee
Apis mellifera
XP_624687
2092
236172
Q54
E
S
S
Q
T
I
S
Q
H
R
S
E
N
E
K
Nematode Worm
Caenorhab. elegans
NP_492790
1634
183268
Sea Urchin
Strong. purpuratus
XP_001195494
2799
311472
K238
D
E
T
D
A
P
W
K
D
M
D
S
S
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
98.7
94.4
N.A.
90.9
91.1
N.A.
N.A.
84.9
N.A.
66.7
54.4
29.4
38.7
27.7
35.5
Protein Similarity:
100
98.1
99.4
96.4
N.A.
95.5
95.3
N.A.
N.A.
90.8
N.A.
77.7
63
42.9
55.5
41.8
49.2
P-Site Identity:
100
13.3
6.6
26.6
N.A.
13.3
13.3
N.A.
N.A.
13.3
N.A.
6.6
0
13.3
6.6
0
13.3
P-Site Similarity:
100
20
20
33.3
N.A.
20
20
N.A.
N.A.
20
N.A.
20
0
26.6
26.6
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
16
0
0
0
0
0
8
0
0
% A
% Cys:
16
0
0
0
0
0
0
8
0
0
0
0
0
16
8
% C
% Asp:
16
39
8
24
0
8
0
0
24
0
8
0
0
0
8
% D
% Glu:
8
8
0
16
0
0
0
8
0
0
8
8
0
8
0
% E
% Phe:
0
0
0
16
8
8
8
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
8
8
0
8
16
0
8
0
% H
% Ile:
0
0
0
0
16
16
31
8
16
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
8
% K
% Leu:
0
0
8
8
8
0
0
8
8
0
24
8
16
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
16
8
8
0
0
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
0
8
0
8
0
0
16
16
8
0
8
8
0
% P
% Gln:
8
8
0
8
0
0
0
24
16
8
0
8
0
8
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
16
39
8
16
24
24
16
0
24
16
39
47
24
31
% S
% Thr:
8
0
24
0
8
8
0
0
0
16
8
0
0
8
0
% T
% Val:
8
0
0
0
16
0
0
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _